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一类用于治疗脑器质性病变的苯并氮杂卓化合物及其制备方法和用途

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10Claims · 4 independent
§ Ⅰ

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Inventor

杨华丽; 程卯生; 赵雪琪; 刘洋

IPC Classification

C07D 491/107 (2006.01)A61P 25/00 (2006.01)A61P 9/10 (2006.01)A61P 25/28 (2006.01)A61K 31/55 (2006.01)

本发明属于药物化学技术领域,本发明涉及一类苯并氮杂卓化合物或其药学上可接受的盐及其制备方法和用途,具体地,本发明公开的化合物结构通式如式(Ⅰ)所示。本发明的苯并氮杂卓化合物在治疗脑器质性病变类疾病,包括血管性病变,退行性病变,特别是血管性痴呆、阿尔兹海默病及胆碱能缺乏相关疾病具有显著疗效。式(Ⅰ)。

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