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CONTRAST ENHANCEMENT FOR MEDICAL IMAGING

发明专利审中
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20权利要求 · 3 独立
§ Ⅰ

卷宗概要

发明人

Paul Roald WESTWICK; Xudong LU; Arthur E. BAILEY; John J.P. FENGLER

IPC 分类

A61B 1/4A61B 1/A61B 1/6A61B 5/A61K 49/

CPC 分类

A61B1/43A61B1/5A61B1/638A61B5/71A61K49/34

A method of visualizing tissue of a subject includes receiving a fluorescence image of the tissue including a plurality of intensity values. A first portion of the intensity values is associated with a first fluorescence emission that is from fluorescence agent that is preferentially accumulated or activated in a target region in the tissue, and a second portion of the intensity values is associated with a second fluorescence emission that is from fluorescence agent that is not located within the target region. The intensity values are analyzed to determine a set of local maximum intensity values. An enhanced fluorescence image is generated by applying a nonlinear contrast mapping based on the set of local maximum intensity values to the plurality of intensity values. The enhanced fluorescence image is displayed, and at least a portion of the target region is diagnosed or treated based on the displayed enhanced fluorescence image.

原文(中文)

A method of visualizing tissue of a subject includes receiving a fluorescence image of the tissue including a plurality of intensity values. A first portion of the intensity values is associated with a first fluorescence emission that is from fluorescence agent that is preferentially accumulated or activated in a target region in the tissue, and a second portion of the intensity values is associated with a second fluorescence emission that is from fluorescence agent that is not located within the target region. The intensity values are analyzed to determine a set of local maximum intensity values. An enhanced fluorescence image is generated by applying a nonlinear contrast mapping based on the set of local maximum intensity values to the plurality of intensity values. The enhanced fluorescence image is displayed, and at least a portion of the target region is diagnosed or treated based on the displayed enhanced fluorescence image.