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THERAPEUTIC AGENT FOR GLAUCOMA COMPRISING FP AGONIST AND ß BLOCKER

发明专利审中
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13权利要求 · 6 独立
§ Ⅰ

卷宗概要

发明人

Shinsaku YAMANE; Satoshi NAKAYAMA; Kazufumi NAGAI; Kazumi MORIYUKI; Tomohiro KARAKAWA

IPC 分类

A61K 31/335A61K 31/138A61K 31/343A61K 31/4704A61K 31/5377A61P 27/6

CPC 分类

A61K31/335A61K31/138A61K31/343A61K31/4704A61K31/5377A61P27/6

A combination of the present invention is an effective therapy for glaucoma, in particular a combination of 2-propanyl 4-{(3S,5aR,6R,7R,8aS)-6-[(1E,3R)-4-(2,5-difluorophenoxy)-3-hydroxy-1-buten-1-yl]-7-hydroxyoctahydro-2H-cyclopenta[b]oxepin-3-yl}butanoate and a β-blocker, is useful as an agent for treating glaucoma since the combination enhances intraocular pressure lowering action compared to a single administration of each drug and has an effect of maintaining intraocular pressure lowering action.

原文(中文)

A combination of the present invention is an effective therapy for glaucoma, in particular a combination of 2-propanyl 4-{(3S,5aR,6R,7R,8aS)-6-[(1E,3R)-4-(2,5-difluorophenoxy)-3-hydroxy-1-buten-1-yl]-7-hydroxyoctahydro-2H-cyclopenta[b]oxepin-3-yl}butanoate and a β-blocker, is useful as an agent for treating glaucoma since the combination enhances intraocular pressure lowering action compared to a single administration of each drug and has an effect of maintaining intraocular pressure lowering action.