CNIPA.AI
返回搜索
档案

ENZYMATIC PROCESS FOR OBTAINING 17 ALPHA-MONOESTERS OF CORTEXOLONE AND/OR ITS 9,11-DEHYDRODERIVATIVES

发明专利审中
21权利要求 · 1 独立
§ Ⅰ

卷宗概要

发明人

Mauro AJANI; Luigi MORO

IPC 分类

A61K 31/573A61K 9/A61K 9/6A61K 47/6A61K 47/10A61K 47/14A61K 47/26A61K 47/44C7J 5/C7J 7/C12P 33/

CPC 分类

A61K31/573A61K9/14A61K9/6A61K47/6A61K47/10A61K47/14A61K47/26A61K47/44C7J5/53C7J7/8C7B2200/13C12P33/5

The present invention refers to a new enzymatic process for obtaining 17α-monoesters of cortexolone and/or its 9,11-dehydroderivatives starting from the corresponding 17α,21-diesters which comprises an enzymatic alcoholysis reaction. Furthermore, the present invention refers to now crystalline forms of cortexolone-17α-propionate and 9,11-dehydro-cortexolone 17α-butanoate.

原文(中文)

The present invention refers to a new enzymatic process for obtaining 17α-monoesters of cortexolone and/or its 9,11-dehydroderivatives starting from the corresponding 17α,21-diesters which comprises an enzymatic alcoholysis reaction. Furthermore, the present invention refers to now crystalline forms of cortexolone-17α-propionate and 9,11-dehydro-cortexolone 17α-butanoate.