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COMPOUNDS, COMPOSITIONS, AND METHODS FOR REDUCING PRODUCTION OF TRIMETHYLAMINE

发明专利审中
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26权利要求 · 1 独立
§ Ⅰ

卷宗概要

发明人

Stanley L. Hazen; James T. Anderson

IPC 分类

A61K 31/724A61K 31/733A61K 45/6C8B 37/C8B 37/16

CPC 分类

A61K31/724A61K31/733A61K45/6C8B37/12C8B37/54

Provided herein are substituted quaternary amine salt compounds and compositions thereof for inhibiting production of trimethylamine (TMA), as well as inhibiting the conversion of choline to trimethylamine, and such compounds, and compositions thereof, utilized for treating for example, kidney disease, diabetes and cardiovascular disease, disorders that are associated with inhibiting the conversion of choline to trimethylamine.

原文(中文)

Provided herein are substituted quaternary amine salt compounds and compositions thereof for inhibiting production of trimethylamine (TMA), as well as inhibiting the conversion of choline to trimethylamine, and such compounds, and compositions thereof, utilized for treating for example, kidney disease, diabetes and cardiovascular disease, disorders that are associated with inhibiting the conversion of choline to trimethylamine.