HYDROCOLLOID-BASED WOUND DRESSINGS AND METHODS FOR THE SAME

原文（中文）

Hydrocolloid-based wound dressings and backing layers thereof are described. The backing layer may include a carrier film prepared from a carrier film composition. The carrier film composition may include a surface active agent and a combination of first and second aromatic polyester-based thermoplastic polyurethanes. The combination of the first and second aromatic polyester-based thermoplastic polyurethanes may provide a wrinkle-free carrier film under accelerated aging conditions. The hydrocolloid-based wound dressing may include an adhesive layer and the backing layer disposed on the adhesive layer. Methods for preparing the backing layer may include contacting the first aromatic polyester-based thermoplastic polyurethane, the second aromatic polyester-based thermoplastic polyurethane, and the surface active agent with one another to prepare a mixture. The method may also include melting and homogenizing the mixture in an extruder, and extrusion casting the melted mixture on the carrier substrate to prepare the backing layer.