MONITORING CLOSED-LOOP NEURAL STIMULATION THERAPY

原文（中文）

An implantable neuromodulation device () that includes a plurality of stimulus electrodes, measurement electrodes, a stimulus source and measurement circuitry (). The device also includes a control unit () configured to: control the stimulus source to provide a neural stimulus to a neural pathway () according to a stimulus intensity parameter; measure an intensity of the evoked neural response in captured signal windows; determine a feedback variable from the measured intensity of the evoked neural response; implement a feedback loop by using the feedback variable to control the stimulus intensity parameter so as to maintain the feedback variable at a target value; convert () a loop variable of the feedback loop to a representation, where the representation is one of a time-domain representation and a frequency-domain representation; and analyse () the representation to determine a loop stability measure of the feedback loop.