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SEQUENTIAL CROSSLINKING WITH HYDROPHOBIC AND HYDROPHILIC CHEMICAL CROSSLINKERS FOR SAMPLE PRESERVATION

发明专利审中
21权利要求 · 6 独立
§ Ⅰ

卷宗概要

发明人

Yang YANG; Kelly MARTIN; Connor KUNIHIRO; Dagmar WALTER; Josephine Y. LEE; Yi LUO; Yinzhou ZHU; Ruijiao XIN

IPC 分类

G1N 1/30C12N 5/

CPC 分类

G1N1/30C12N5/528G1N2001/305

Methods and kits for sample preparation are provided, wherein a sample comprising at least one cell or tissue is contacted sequentially with a hydrophobic crosslinker, and then a hydrophilic crosslinker. The method prevents cell and tissue analytes from diffusing out of the at least one cell or tissue, such that the cell and tissue analytes can be analyzed and/or imaged.

原文(中文)

Methods and kits for sample preparation are provided, wherein a sample comprising at least one cell or tissue is contacted sequentially with a hydrophobic crosslinker, and then a hydrophilic crosslinker. The method prevents cell and tissue analytes from diffusing out of the at least one cell or tissue, such that the cell and tissue analytes can be analyzed and/or imaged.