DIAGNOSTIC ENGINEERED IMMUNE SKEWING MODEL FOR PREDICTIVE CANCER METASTASIS
卷宗概要
申请人
The Trustees of Columbia University in the City of New York
发明人
Daniel Naveed TAVAKOL; Gordana VUNJAK-NOVAKOVIC; Pamela L. GRANEY
IPC 分类
CPC 分类
Models and methods are provided for non-invasive diagnostic and predictive assessment of the systemic effects of metastasis in a human based on a tissue engineered immune system. Characterization of changes to bone marrow resulting from the presence and progression of a primary breast tumor including skewing of blood/immune cells at various phenotypes of cancer progression, and its use in assessing the metastatic state of a subject and/or the effects of candidate drugs thereon.
原文（中文）
Models and methods are provided for non-invasive diagnostic and predictive assessment of the systemic effects of metastasis in a human based on a tissue engineered immune system. Characterization of changes to bone marrow resulting from the presence and progression of a primary breast tumor including skewing of blood/immune cells at various phenotypes of cancer progression, and its use in assessing the metastatic state of a subject and/or the effects of candidate drugs thereon.