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TREATING PATIENTS HARBORING AN ISOCITRATE DEHYDROGENASE-1 (IDH-1) MUTATION
发明专利审中
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22权利要求 · 2 独立
§ Ⅰ
卷宗概要
发明人
Patrick F. Kelly; Alan Collis; Jeff Davis; Duncan Walker; Susan Ashwell; Blythe Thomson; Wei Lu
IPC 分类
A61K 31/4709A61P 35/2C12Q 1/686C12Q 1/6886
CPC 分类
A61K31/4709A61P35/2C12Q1/686C12Q1/6886C12Q2531/113C12Q2561/113C12Q2600/156
Methods of treating patients diagnosed with AML or MDS harboring mutant IDH-1 include detecting an IDH1 mutation and the therapeutic administration of an inhibitor of a mutant IDH-1 as a single agent, or in combination with azacitidine (AZA) or cytarabine.
原文（中文）
Methods of treating patients diagnosed with AML or MDS harboring mutant IDH-1 include detecting an IDH1 mutation and the therapeutic administration of an inhibitor of a mutant IDH-1 as a single agent, or in combination with azacitidine (AZA) or cytarabine.