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ROCK INHIBITORS AND USES THEREOF

发明专利审中
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22权利要求 · 4 独立
§ Ⅰ

卷宗概要

发明人

Casey Casimir Kopczynski; Jill Marie Sturdivant; Michael Scott McClure; Anjali Biren Joshi

IPC 分类

C7D 217/2A61K 9/A61K 31/472A61K 31/5575A61K 47/2A61K 47/18A61K 47/26A61P 27/6A61P 27/14

CPC 分类

C7D217/2A61K9/48A61K31/472A61K31/5575A61K47/2A61K47/186A61K47/26A61P27/6A61P27/14

Provided herein are compounds comprising a formula of 4-(3-amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)benzyl adamantane carboxylate (e.g., compounds of formula (I) or formula (II)) or a pharmaceutically acceptable salt thereof. The compounds are useful for reducing intraocular pressure and for treating glaucoma or ocular hypertension.

原文(中文)

Provided herein are compounds comprising a formula of 4-(3-amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)benzyl adamantane carboxylate (e.g., compounds of formula (I) or formula (II)) or a pharmaceutically acceptable salt thereof. The compounds are useful for reducing intraocular pressure and for treating glaucoma or ocular hypertension.