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METHOD OF TREATING OR AMELIORATING METABOLIC DISORDERS USING BINDING PROTEINS FOR GASTRIC INHIBITORY PEPTIDE RECEPTOR (GIPR) IN COMBINATION WITH GLP-1 AGONISTS

发明专利审中
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24权利要求 · 8 独立
§ Ⅰ

卷宗概要

发明人

Darren L. BATES; Donghui SHI; David J. LLOYD; Pavel BONDARENKO; Mark L. MICHAELS; Todd HAGER; Xiaoshan MIN; Aiko UMEDA; Irwin CHEN; Zhulun WANG

IPC 分类

C7K 16/28A61K 9/A61K 38/26

CPC 分类

C7K16/2869A61K38/26A61K9/19C7K2317/21C7K2317/54C7K2317/55

Methods of treating metabolic diseases and disorders using an antigen binding protein specific for the GIPR polypeptide are provided. In various embodiments the metabolic disease or disorder is type 2 diabetes, obesity, dyslipidemia, elevated glucose levels, elevated insulin levels and diabetic nephropathy. In certain embodiments the antigen binding protein is administered in combination with a GLP-1 receptor agonist.

原文(中文)

Methods of treating metabolic diseases and disorders using an antigen binding protein specific for the GIPR polypeptide are provided. In various embodiments the metabolic disease or disorder is type 2 diabetes, obesity, dyslipidemia, elevated glucose levels, elevated insulin levels and diabetic nephropathy. In certain embodiments the antigen binding protein is administered in combination with a GLP-1 receptor agonist.