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DEVICES AND METHODS FOR CELL AGGREGATION

发明专利审中
86权利要求 · 2 独立
§ Ⅰ

卷宗概要

发明人

Thomas Jay LOWERY, JR.; Christopher Garrison WILSON; William SCHOLL; Marcus LEHMANN; Christopher MONTALBANO; Greg MONTALBANO; Andrew MARTIN

IPC 分类

C12M 1/32C12M 1/C12M 1/12

CPC 分类

C12M23/12C12M23/40C12M25/6C12M29/

Featured is a device for aggregating populations of cells that includes one or more plates that include a microwell film composite. The microwell film composite includes a first layer with a plurality of microwells and a second layer that includes a permeable body that includes a plurality of pores. The device further includes one or more ports for fluid input and/or output. Also featured are methods of making aggregates including a first population of cells (e.g., parenchymal cells (e.g., hepatocytes)) and a second population of cells (e.g., stromal cells).

原文(中文)

Featured is a device for aggregating populations of cells that includes one or more plates that include a microwell film composite. The microwell film composite includes a first layer with a plurality of microwells and a second layer that includes a permeable body that includes a plurality of pores. The device further includes one or more ports for fluid input and/or output. Also featured are methods of making aggregates including a first population of cells (e.g., parenchymal cells (e.g., hepatocytes)) and a second population of cells (e.g., stromal cells).