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COMPOSITION AND METHOD FOR EX VIVO EXPANSION OF STEM CELL MEMORY T CELLS

发明专利审中
8权利要求 · 2 独立
§ Ⅰ

卷宗概要

发明人

Wei Hua CHU; Ting-Yun LIU; Pei-Yi LIN

IPC 分类

C12N 5/783C12N 5/

CPC 分类

C12N5/636C12N5/18C12N2500/33C12N2500/84C12N2501/2307C12N2501/2315C12N2523/

The composition and method for ex vivo expansion of stem cell memory T cells provided by the embodiments of the present disclosure can amplify and culture a cell population with a higher proportion of memory T stem cells, a higher combined proportion of memory T stem cells and central memory T cells, and a higher proportion of natural killer T cells compared to other processes. Additionally, the obtained cell population demonstrates excellent cytotoxic effects against bone cancer and pancreatic cancer cell lines, leading to the production of cell products with enhanced cell therapy efficacy.

原文(中文)

The composition and method for ex vivo expansion of stem cell memory T cells provided by the embodiments of the present disclosure can amplify and culture a cell population with a higher proportion of memory T stem cells, a higher combined proportion of memory T stem cells and central memory T cells, and a higher proportion of natural killer T cells compared to other processes. Additionally, the obtained cell population demonstrates excellent cytotoxic effects against bone cancer and pancreatic cancer cell lines, leading to the production of cell products with enhanced cell therapy efficacy.