SIRNA TARGETING AND REGULATING PCSK9 GENE EXPRESSION AND USE THEREOF
卷宗概要
申请人
Hangzhou Tianlong Pharmaceutical Co., Ltd.
发明人
Gengshen SONG; Zeao HUANG; Shuo YANG; Zhikang TIAN; Yucheng WU; Peng YAO; Xiaowen YU; Dawei HUANG; Xue PANG; Fang LIN
IPC 分类
CPC 分类
The present disclosure relates to siRNAs that target and regulate PCSK9 gene expression and use thereof. Experimental results show that some alternately modified and specific template-modified oligonucleotide sequences can significantly inhibit PCSK9 expression and can be used to develop drugs to treat PCSK9-related diseases.
原文（中文）
The present disclosure relates to siRNAs that target and regulate PCSK9 gene expression and use thereof. Experimental results show that some alternately modified and specific template-modified oligonucleotide sequences can significantly inhibit PCSK9 expression and can be used to develop drugs to treat PCSK9-related diseases.