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Immune Classification Tool for Determining Survival Outcomes in Cancer

发明专利审中
21权利要求 · 3 独立
§ Ⅰ

卷宗概要

申请人

London Health Sciences Centre Research Inc.; The Regents of the University of California

发明人

Yu Fan Zeng; Anthony Nichols; John Barrett; Paul Boutros; Joseph Mymryk

IPC 分类

C12Q 1/6886

CPC 分类

C12Q1/6886C12Q2600/112C12Q2600/118C12Q2600/158

An immune classification tool useful for determining survival outcomes in cancer patients based on the abundance in gene expression of CD3E, ZAP70 and IRF4 in a cancer tissue sample. The immune classification tool is able to stratify cancer patients, including HPV+HNSCC, HPV−HNSCC and cervical cancer patients, into the three immune groups (immune rich, immune desert, and mixed) that are strongly associated with disease-free survival.

原文(中文)

An immune classification tool useful for determining survival outcomes in cancer patients based on the abundance in gene expression of CD3E, ZAP70 and IRF4 in a cancer tissue sample. The immune classification tool is able to stratify cancer patients, including HPV+HNSCC, HPV−HNSCC and cervical cancer patients, into the three immune groups (immune rich, immune desert, and mixed) that are strongly associated with disease-free survival.