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METHOD FOR ESTIMATING CAUSE OF PROLONGATION OF BLOOD CLOTTING TIME, AND INFORMATION PROCESSING DEVICE

发明专利审中
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25权利要求 · 11 独立
§ Ⅰ

卷宗概要

发明人

Hiroyuki MINEMURA; Kyoko YAMAMOTO; Chie YABUTANI; Mariko UMEDA

IPC 分类

G1N 21/77G1N 33/86

CPC 分类

G1N21/77G1N33/86

A cause of prolongation of a blood clotting time for a test sample is estimated by acquiring a clot waveform showing a change in light amount over time according to a coagulation reaction of a reaction liquid. A first waveform is acquired by performing before-after differentiation processing on the clot waveform. First and second fitted waveforms are acquired by performing fitting processing on the clot waveform and the first waveform. A third waveform is acquired by performing before-after differentiation processing on the second fitted waveform. First to third normalized waveforms are acquired by normalizing the first and second fitted waveforms and the third waveform, respectively, on a light amount axis and a time axis. A feature from each of the first to third normalized waveforms is extracted; and the cause of prolongation of a blood clotting time is estimated based on a known feature and the extracted feature.

原文(中文)

A cause of prolongation of a blood clotting time for a test sample is estimated by acquiring a clot waveform showing a change in light amount over time according to a coagulation reaction of a reaction liquid. A first waveform is acquired by performing before-after differentiation processing on the clot waveform. First and second fitted waveforms are acquired by performing fitting processing on the clot waveform and the first waveform. A third waveform is acquired by performing before-after differentiation processing on the second fitted waveform. First to third normalized waveforms are acquired by normalizing the first and second fitted waveforms and the third waveform, respectively, on a light amount axis and a time axis. A feature from each of the first to third normalized waveforms is extracted; and the cause of prolongation of a blood clotting time is estimated based on a known feature and the extracted feature.