Display substrate and display device

A display substrate and a display device wherein the display substrate comprises: a substrate and a drive circuit layer arranged on the substrate, the substrate comprises: a display area (100) and a non-display area (200), the drive circuit layer comprises: a pixel drive circuit (PE) located in the display area (100), and a gate drive circuit and at least one initial power supply line located in the non-display area (200), the initial supply line extends at least partially in a first direction (D1); the gate driving circuit is configured to provide a driving signal to the pixel driving circuit (PE), and the initial power supply line is configured to provide an initial signal to the pixel driving circuit (PE); the orthographic projection of at least one initial power supply line on the substrate is at least partially overlapped with the orthographic projection of the gate drive circuit on the substrate.