CONTRAST ENHANCEMENT FOR MEDICAL IMAGING

原文（中国語）

A method of visualizing tissue of a subject includes receiving a fluorescence image of the tissue including a plurality of intensity values. A first portion of the intensity values is associated with a first fluorescence emission that is from fluorescence agent that is preferentially accumulated or activated in a target region in the tissue, and a second portion of the intensity values is associated with a second fluorescence emission that is from fluorescence agent that is not located within the target region. The intensity values are analyzed to determine a set of local maximum intensity values. An enhanced fluorescence image is generated by applying a nonlinear contrast mapping based on the set of local maximum intensity values to the plurality of intensity values. The enhanced fluorescence image is displayed, and at least a portion of the target region is diagnosed or treated based on the displayed enhanced fluorescence image.