Methods for Improving Macular Pigment Optical Density Measurement by Accounting for Melanin Absorption Using Heterochromatic Flicker Photometry (HFP)

原文（中国語）

The present invention relates to methods for measuring macular pigment optical density (MPOD) more accurately by accounting for melanin absorption. Traditional heterochromatic flicker photometry (HFP) techniques do not consider melanin, leading to inaccuracies. This patent introduces two novel methods to correct for melanin absorption: (1) adding an additional LED wavelength around 600 nm that is absorbed by melanin but not by macular pigment, and (2) replacing the green LED in the traditional HFP setup with a red LED that is absorbed by melanin but not by macular pigment. These methods improve the accuracy of MPOD measurements, providing more reliable data for clinical and research applications.