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案件記録
HISTONE DEACETYLASE INHIBITORS FOR USE IN IMMUNOTHERAPY
発明審査中
10請求項 · 1 独立
§ Ⅰ
案件概要
発明者
James N. WOODY
IPC分類
A61K 31/522A61K 9/A61K 31/4709A61K 31/506A61K 38/15A61K 38/17A61K 39/A61K 39/395A61K 40/11A61K 40/31A61K 40/46A61K 45/6A61P 31/22A61P 35/A61P 35/4C12N 9/80
CPC分類
A61K31/522A61K9/53A61K31/4709A61K31/506A61K38/15A61K38/177A61K38/1774A61K39/3955A61K39/39558A61K40/11A61K40/31A61K40/46A61K45/6A61P31/22A61P35/A61P35/4C12N9/80A61K2039/505A61K2239/31A61K2239/38A61K2239/48A61K2239/51
Provided are methods and compositions for the treatment of cancer. The methods comprise administering to a subject an HDAC inhibitor and an immunotherapeutic. In certain instances the immunotherapeutic is a chimeric antigen receptor T cell, an antibody or polypeptide that binds a checkpoint inhibitor, or a vaccine.
原文（中国語）
Provided are methods and compositions for the treatment of cancer. The methods comprise administering to a subject an HDAC inhibitor and an immunotherapeutic. In certain instances the immunotherapeutic is a chimeric antigen receptor T cell, an antibody or polypeptide that binds a checkpoint inhibitor, or a vaccine.
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