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案件記録

COMPOUNDS, COMPOSITIONS, AND METHODS FOR REDUCING PRODUCTION OF TRIMETHYLAMINE

発明審査中
26請求項 · 1 独立
§ Ⅰ

案件概要

発明者

Stanley L. Hazen; James T. Anderson

IPC分類

A61K 31/724A61K 31/733A61K 45/6C8B 37/C8B 37/16

CPC分類

A61K31/724A61K31/733A61K45/6C8B37/12C8B37/54

Provided herein are substituted quaternary amine salt compounds and compositions thereof for inhibiting production of trimethylamine (TMA), as well as inhibiting the conversion of choline to trimethylamine, and such compounds, and compositions thereof, utilized for treating for example, kidney disease, diabetes and cardiovascular disease, disorders that are associated with inhibiting the conversion of choline to trimethylamine.

原文(中国語)

Provided herein are substituted quaternary amine salt compounds and compositions thereof for inhibiting production of trimethylamine (TMA), as well as inhibiting the conversion of choline to trimethylamine, and such compounds, and compositions thereof, utilized for treating for example, kidney disease, diabetes and cardiovascular disease, disorders that are associated with inhibiting the conversion of choline to trimethylamine.

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