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案件記録

IN VIVO TRANSITION METAL DETECTION

発明審査中
6閲覧数
33請求項 · 14 独立
§ Ⅰ

案件概要

発明者

Elizabeth NEW; Kay DOUBLE; Marcus GRAZIOTTO; Liam ADAIR

IPC分類

A61K 51/4A61B 5/A61B 6/3A61B 6/50A61K 49/

CPC分類

A61K51/482A61B5/71A61B6/37A61B6/501A61K49/21A61K49/52A61K2123/

The present invention is directed to a probe for detecting a transition metal, the probe comprising: a metal chelating portion configured to coordinate with a transition metal; a label portion configured to be detectable; and a linker bound to both the metal chelating portion and the label portion, wherein the linker is configured to react with a nucleophile when the metal chelating portion coordinates with the transition metal, as well in vivo and in vitro methods and uses thereof.

原文(中国語)

The present invention is directed to a probe for detecting a transition metal, the probe comprising: a metal chelating portion configured to coordinate with a transition metal; a label portion configured to be detectable; and a linker bound to both the metal chelating portion and the label portion, wherein the linker is configured to react with a nucleophile when the metal chelating portion coordinates with the transition metal, as well in vivo and in vitro methods and uses thereof.

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