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案件記録

NOVEL B0AT1 INHIBITOR

発明審査中
8閲覧数
21請求項 · 1 独立
§ Ⅰ

案件概要

発明者

Takuya IMAZU; Kazuki NAKAYAMA; Kazunari SHIMOOKA

IPC分類

C7D 217/6C7D 209/8C7D 241/4C7D 471/4C7D 495/4C7D 513/4

CPC分類

C7D217/6C7D209/8C7D241/4C7D471/4C7D495/4C7D513/4

The present invention relates to a compound having a BOAT1 inhibitory action and represented by the following formula (I): wherein each symbol is as defined in the specification, or a salt thereof. In addition, the present invention relates to a BOAT1 inhibitor containing the aforementioned compound and a pharmaceutical composition containing the aforementioned compound. One embodiment of the present invention is, for example, a medicament preferable for the prophylaxis and/or treatment of amino acid metabolism disorders such as phenylketonuria, urea cycle disorder, hypertyrosinemia (types 1-3), hypermethioninemia, maple syrup urine disease, homocystinuria, nonketotic hyperglycinemia, propionic acidemia, methylmalonic acidemia, isovaleric acidemia and the like.

原文(中国語)

The present invention relates to a compound having a BOAT1 inhibitory action and represented by the following formula (I): wherein each symbol is as defined in the specification, or a salt thereof. In addition, the present invention relates to a BOAT1 inhibitor containing the aforementioned compound and a pharmaceutical composition containing the aforementioned compound. One embodiment of the present invention is, for example, a medicament preferable for the prophylaxis and/or treatment of amino acid metabolism disorders such as phenylketonuria, urea cycle disorder, hypertyrosinemia (types 1-3), hypermethioninemia, maple syrup urine disease, homocystinuria, nonketotic hyperglycinemia, propionic acidemia, methylmalonic acidemia, isovaleric acidemia and the like.

外部リソース