METHODS AND COMPOSITIONS OF INHIBITING DCN1-UBC12 INTERACTION
案件概要
出願人
University of Kentucky Research Foundation
発明者
Leah C. Kovalic; Tucker J. Moseley; R. Kip Guy
IPC分類
CPC分類
A compound is provided that is a modified piperidinyl urea-based inhibitors of DCN1-UBE2M interaction, abridged or unbridged NAcM-OPT derivative compound, or a bridged and unbridged isoquinoline carboxamide derivative compound, or a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprising the compound, or a pharmaceutically acceptable salt thereof, is provided. Methods for treating diseases or disorders characterized by uncontrolled cellular proliferation are described including administering the compound, pharmaceutically acceptable salt thereof, or pharmaceutical composition comprising the compound or pharmaceutically acceptable salt thereof to a subject in need thereof.
原文（中国語）
A compound is provided that is a modified piperidinyl urea-based inhibitors of DCN1-UBE2M interaction, abridged or unbridged NAcM-OPT derivative compound, or a bridged and unbridged isoquinoline carboxamide derivative compound, or a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprising the compound, or a pharmaceutically acceptable salt thereof, is provided. Methods for treating diseases or disorders characterized by uncontrolled cellular proliferation are described including administering the compound, pharmaceutically acceptable salt thereof, or pharmaceutical composition comprising the compound or pharmaceutically acceptable salt thereof to a subject in need thereof.
外部リソース