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案件記録

IMPROVED METHODS OF PREPARING DIFFERENT MESODERM CELL TYPES

発明審査中
1閲覧数
27請求項 · 7 独立
§ Ⅰ

案件概要

発明者

Aaron M. ZORN; Lu HAN; Keishi KISHIMOTO; Mitsuru MORIMOTO

IPC分類

C12N 5/73

CPC分類

C12N5/603C12N2500/38C12N2501/115C12N2501/15C12N2501/155C12N2501/415C12N2506/45

Disclosed herein are improved in vitro methods of making splanchnic mesoderm cell types and subtypes thereof from pluripotent cells. These methods can be used to produced improved foregut- and hindgut-derived organoids containing enriched mesenchyme, which enhances organoid viability, growth, and maturation, both in in vitro culture and in vivo transplantation.

原文(中国語)

Disclosed herein are improved in vitro methods of making splanchnic mesoderm cell types and subtypes thereof from pluripotent cells. These methods can be used to produced improved foregut- and hindgut-derived organoids containing enriched mesenchyme, which enhances organoid viability, growth, and maturation, both in in vitro culture and in vivo transplantation.

外部リソース