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案件記録

GENERATION OF CTL LINES WITH SPECIFICITY AGAINST MULTIPLE TUMOR ANTIGENS OR MULTIPLE VIRUSES

発明審査中
1閲覧数
11請求項 · 2 独立
§ Ⅰ

案件概要

発明者

Ann Marie Leen; Ulrike Gerdemann; Cliona M. Rooney; Juan F. Vera Valdes; John R. Wilson

IPC分類

C12N 5/783A61K 39/A61K 39/12A61K 39/155A61K 39/245A61K 40/11A61K 40/22A61K 40/41A61K 40/42A61K 40/46

CPC分類

C12N5/636A61K39/12A61K39/155A61K39/245A61K40/11A61K40/22A61K40/418A61K40/424A61K40/4266A61K40/4267A61K40/4268A61K40/4269A61K40/427A61K40/4273A61K40/46C12N5/638A61K2039/54A61K2039/572A61K2239/31A61K2239/38A61K2239/48C12N2501/23C12N2501/2302C12N2501/2306C12N2501/2307C12N2501/2312C12N2501/2315C12N2502/11

The present invention encompasses methods and compositions for the generation and use of cytotoxic T lymphocytes that target multiple viruses or that are specific for multiple tumor antigens. In specific embodiments, the generation methods employ use of certain cytokines to promote proliferation and reduce cell death in an activated T cell population and/or that employ a particular bioreactor having a gas permeable membrane.

原文(中国語)

The present invention encompasses methods and compositions for the generation and use of cytotoxic T lymphocytes that target multiple viruses or that are specific for multiple tumor antigens. In specific embodiments, the generation methods employ use of certain cytokines to promote proliferation and reduce cell death in an activated T cell population and/or that employ a particular bioreactor having a gas permeable membrane.

外部リソース