PERSONALIZED TUMOR MARKERS
案件概要
出願人
Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis; Stichting VU
発明者
Gerrit Albert MEIJER; Evert VAN DEN BROEK; Remondus Johannes Adriaan FIJNEMAN; Sanne ABELN; Soufyan LAKBIR; Jakob HERINGA
IPC分類
CPC分類
The invention relates to methods for tumor marker analysis comprising providing a genomic DNA sample from tumor cells of a patient, preselecting a chromosomal region on the genomic DNA comprising at least part of a potential structural variant (SV); and sequencing the genomic region to characterize the potential SV. The invention further relates to methods for detecting minimal residual disease, monitoring treatment response and tumor progression in a patient by employing the SV, and to personalized therapy based on the identity of the SV.
原文（中国語）
The invention relates to methods for tumor marker analysis comprising providing a genomic DNA sample from tumor cells of a patient, preselecting a chromosomal region on the genomic DNA comprising at least part of a potential structural variant (SV); and sequencing the genomic region to characterize the potential SV. The invention further relates to methods for detecting minimal residual disease, monitoring treatment response and tumor progression in a patient by employing the SV, and to personalized therapy based on the identity of the SV.
外部リソース