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案件記録

IMAGING FLOW CYTOMETRY-BASED HIGH-THROUGHPUT DRUG SCREENING METHOD

発明審査中
1閲覧数
9請求項 · 1 独立
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案件概要

発明者

Jingjing ZHAO; Lin DU

IPC分類

G1N 15/1434G1N 1/30G1N 15/1G1N 15/10G1N 15/1404G1N 15/1433G1N 33/58

CPC分類

G1N15/1434G1N1/30G1N15/1G1N15/1404G1N15/1433G1N33/582G1N2015/1006G1N2015/144G1N2500/10

An imaging flow cytometry-based high-throughput drug screening method, comprising: cell incubation, cell staining, acquiring single-cell images by using a flow cytometer, and image extraction and analysis, which combines the high-throughput advantages of flow cytometry and the imaging capability of a microscope, so that multi-channel single-cell images can be generated in a high throughput manner, thereby implementing acquisition of fluorescent images and unmarked images of single cells at a throughput of 102-105 cells per second, which can be used for cell phenotype drug screening and improving the screening efficiency by a factor of 102-104.

原文(中国語)

An imaging flow cytometry-based high-throughput drug screening method, comprising: cell incubation, cell staining, acquiring single-cell images by using a flow cytometer, and image extraction and analysis, which combines the high-throughput advantages of flow cytometry and the imaging capability of a microscope, so that multi-channel single-cell images can be generated in a high throughput manner, thereby implementing acquisition of fluorescent images and unmarked images of single cells at a throughput of 102-105 cells per second, which can be used for cell phenotype drug screening and improving the screening efficiency by a factor of 102-104.

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