DIAGNOSTIC ENGINEERED IMMUNE SKEWING MODEL FOR PREDICTIVE CANCER METASTASIS
案件概要
出願人
The Trustees of Columbia University in the City of New York
発明者
Daniel Naveed TAVAKOL; Gordana VUNJAK-NOVAKOVIC; Pamela L. GRANEY
IPC分類
CPC分類
Models and methods are provided for non-invasive diagnostic and predictive assessment of the systemic effects of metastasis in a human based on a tissue engineered immune system. Characterization of changes to bone marrow resulting from the presence and progression of a primary breast tumor including skewing of blood/immune cells at various phenotypes of cancer progression, and its use in assessing the metastatic state of a subject and/or the effects of candidate drugs thereon.
原文(中国語)
Models and methods are provided for non-invasive diagnostic and predictive assessment of the systemic effects of metastasis in a human based on a tissue engineered immune system. Characterization of changes to bone marrow resulting from the presence and progression of a primary breast tumor including skewing of blood/immune cells at various phenotypes of cancer progression, and its use in assessing the metastatic state of a subject and/or the effects of candidate drugs thereon.
外部リソース