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案件記録

DIAGNOSTIC ENGINEERED IMMUNE SKEWING MODEL FOR PREDICTIVE CANCER METASTASIS

発明審査中
14請求項 · 2 独立
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案件概要

発明者

Daniel Naveed TAVAKOL; Gordana VUNJAK-NOVAKOVIC; Pamela L. GRANEY

IPC分類

G1N 33/50A61B 10/C12N 5/9

CPC分類

G1N33/5011C12N5/693G1N33/5082A61B10/41C12N2503/4C12N2513/C12N2533/90

Models and methods are provided for non-invasive diagnostic and predictive assessment of the systemic effects of metastasis in a human based on a tissue engineered immune system. Characterization of changes to bone marrow resulting from the presence and progression of a primary breast tumor including skewing of blood/immune cells at various phenotypes of cancer progression, and its use in assessing the metastatic state of a subject and/or the effects of candidate drugs thereon.

原文(中国語)

Models and methods are provided for non-invasive diagnostic and predictive assessment of the systemic effects of metastasis in a human based on a tissue engineered immune system. Characterization of changes to bone marrow resulting from the presence and progression of a primary breast tumor including skewing of blood/immune cells at various phenotypes of cancer progression, and its use in assessing the metastatic state of a subject and/or the effects of candidate drugs thereon.

外部リソース