SYNTHETIC RETINOIDS FOR USE IN RAR ACTIVATION
개요
발명자
Andrew Whiting; David Chisholm; Iain Greig; Thabat Khatib; Peter McCaffery
IPC 분류
CPC 분류
The present invention relates to compounds of formula I: in which A-Aand Rto Rare defined herein, for use in the treatment of a condition or disease which is alleviated by the activation of retinoic acid receptors (RAR). The invention also relates to pharmaceutical compounds comprising such compounds, and related methods of treatment. In an aspect, the invention relates to a method of screening compounds for therapeutic potential in the treatment of a condition or disease which is alleviated by the activation of retinoic acid receptors (RAR). Aspects of the invention relate to novel compounds of formula I in which at least one of Ato Ais N or at least one of Ais CRor Ais CRin which R/Ris halogen.
원문 (중국어)
The present invention relates to compounds of formula I: in which A-Aand Rto Rare defined herein, for use in the treatment of a condition or disease which is alleviated by the activation of retinoic acid receptors (RAR). The invention also relates to pharmaceutical compounds comprising such compounds, and related methods of treatment. In an aspect, the invention relates to a method of screening compounds for therapeutic potential in the treatment of a condition or disease which is alleviated by the activation of retinoic acid receptors (RAR). Aspects of the invention relate to novel compounds of formula I in which at least one of Ato Ais N or at least one of Ais CRor Ais CRin which R/Ris halogen.