Substituted N-(Pyridin-2-yl)Acetamide Derivatives as CDK12/13 Inhibitors
개요
발명자
Ramulu Poddutoori; Susanta Samajdar; Subhendu Mukherjee; Suraj Tatyasaheb Gore; Devaraja Thimmasandra Seethappa; Paul Gillespie; Scott Simonovich
IPC 분류
CPC 분류
The present application provides substituted N-(pyridin-2-yl)acetamide derivatives of formula (I) which are therapeutically useful as CDK12/13 inhibitors. These compounds are useful in the treatment and/or prevention of diseases and/or disorders associated with CDK12/13 in a mammal. In addition, the present application provides preparation of the compounds and pharmaceutical compositions comprising at least one of the substituted N-(pyridin-2-yl)acetamide derivatives of formula (I) or a pharmaceutically acceptable salt, an N-oxide or a stereoisomer thereof.
원문 (중국어)
The present application provides substituted N-(pyridin-2-yl)acetamide derivatives of formula (I) which are therapeutically useful as CDK12/13 inhibitors. These compounds are useful in the treatment and/or prevention of diseases and/or disorders associated with CDK12/13 in a mammal. In addition, the present application provides preparation of the compounds and pharmaceutical compositions comprising at least one of the substituted N-(pyridin-2-yl)acetamide derivatives of formula (I) or a pharmaceutically acceptable salt, an N-oxide or a stereoisomer thereof.