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COMPOUNDS, COMPOSITIONS, AND METHODS FOR REDUCING PRODUCTION OF TRIMETHYLAMINE

발명심사 중
6조회수
26청구항 · 1 독립항
§ Ⅰ

개요

발명자

Stanley L. Hazen; James T. Anderson

IPC 분류

A61K 31/724A61K 31/733A61K 45/6C8B 37/C8B 37/16

CPC 분류

A61K31/724A61K31/733A61K45/6C8B37/12C8B37/54

Provided herein are substituted quaternary amine salt compounds and compositions thereof for inhibiting production of trimethylamine (TMA), as well as inhibiting the conversion of choline to trimethylamine, and such compounds, and compositions thereof, utilized for treating for example, kidney disease, diabetes and cardiovascular disease, disorders that are associated with inhibiting the conversion of choline to trimethylamine.

원문 (중국어)

Provided herein are substituted quaternary amine salt compounds and compositions thereof for inhibiting production of trimethylamine (TMA), as well as inhibiting the conversion of choline to trimethylamine, and such compounds, and compositions thereof, utilized for treating for example, kidney disease, diabetes and cardiovascular disease, disorders that are associated with inhibiting the conversion of choline to trimethylamine.