IN VIVO TRANSITION METAL DETECTION
개요
발명자
Elizabeth NEW; Kay DOUBLE; Marcus GRAZIOTTO; Liam ADAIR
IPC 분류
CPC 분류
The present invention is directed to a probe for detecting a transition metal, the probe comprising: a metal chelating portion configured to coordinate with a transition metal; a label portion configured to be detectable; and a linker bound to both the metal chelating portion and the label portion, wherein the linker is configured to react with a nucleophile when the metal chelating portion coordinates with the transition metal, as well in vivo and in vitro methods and uses thereof.
원문 (중국어)
The present invention is directed to a probe for detecting a transition metal, the probe comprising: a metal chelating portion configured to coordinate with a transition metal; a label portion configured to be detectable; and a linker bound to both the metal chelating portion and the label portion, wherein the linker is configured to react with a nucleophile when the metal chelating portion coordinates with the transition metal, as well in vivo and in vitro methods and uses thereof.