COMPOUND OR SALT THEREOF, LIPID COMPOSITION, PHARMACEUTICAL COMPOSITION, AND DELIVERY CARRIER

원문 (중국어)

A compound or a salt thereof which facilitates the introduction of a nucleic acid into a cell or the like is provided. Also provided are a lipid composition, a pharmaceutical composition, and a delivery carrier which employ the compound or a salt thereof, and which are capable of realizing a high nucleic acid encapsulation rate and excellent nucleic acid delivery in a case where mRNA is used. Thus, a compound represented by Formula (1) or a salt thereof is provided, wherein Rrepresents a hydrocarbon group having 1 to 24 carbon atoms, Rrepresents a hydrocarbon group having 1 to 6 carbon atoms, Rrepresents a hydrocarbon group having 6 to 24 carbon atoms and having a branched chain, Rand Rrepresent a hydrocarbon group having 1 to 6 carbon atoms, which may be substituted, Rrepresents a hydrogen atom or a hydrocarbon group having 1 to 18 carbon atoms, L represents *—O—C(O)— or *—C(O)O—, a represents an integer of 1 to 12, and b, c, and d represent an integer of 1 to 4. S