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기록

HETEROCYCLIC COMPOUND CAPABLE OF INHIBITING PRMT5-MTA AND USE THEREOF

발명심사 중
4조회수
16청구항 · 3 독립항
§ Ⅰ

개요

발명자

Yao LI; Haoliang ZHANG; Zongjun SHI; Jiancheng WANG; Long WANG; Naicheng GUI; Jingzheng ZHAO; Shuai HUANG; Pingming TANG; Chen ZHANG; Pangke YAN

IPC 분류

C7D 403/14A61K 31/422A61K 31/4375A61K 31/4709A61K 31/4725A61K 31/4745A61K 31/502A61K 31/5025A61K 31/513A61K 31/517A61K 31/519A61K 31/549A61P 35/C7D 401/4C7D 401/14C7D 403/4C7D 403/6C7D 413/4C7D 413/10C7D 417/4C7D 471/4C7D 487/4C7D 495/4C7D 498/4C7D 513/4

CPC 분류

C7D403/14A61K31/422A61K31/4375A61K31/4709A61K31/4725A61K31/4745A61K31/502A61K31/5025A61K31/513A61K31/517A61K31/519A61K31/549A61P35/C7D401/4C7D401/14C7D403/4C7D403/6C7D413/4C7D413/10C7D417/4C7D471/4C7D487/4C7D495/4C7D498/4C7D513/4

A nitrogen-containing heterocyclic compound represented by formula (I-a), or a stereoisomer, a deuterated compound, a solvate, a pharmaceutically acceptable salt or a eutectic crystal thereof, a pharmaceutical composition comprising same, and a use thereof in the preparation of a drug for treating/preventing PRMT5⋅MTA-mediated diseases, wherein each group in formula (I-a) is as defined in the description.

원문 (중국어)

A nitrogen-containing heterocyclic compound represented by formula (I-a), or a stereoisomer, a deuterated compound, a solvate, a pharmaceutically acceptable salt or a eutectic crystal thereof, a pharmaceutical composition comprising same, and a use thereof in the preparation of a drug for treating/preventing PRMT5⋅MTA-mediated diseases, wherein each group in formula (I-a) is as defined in the description.