SYSTEMS AND PROCESSES FOR SKIN TISSUE GROWTH AND ANALYSIS

원문 (중국어)

This disclosure relates to skin tissue systems, devices, and methods. Systems described include ones comprising: a tissue sample; an insert; and a porous layer configured to promote mass transport into the tissue sample; wherein the skin tissue system is capable of supporting tissue viability for at least one week. Methods described include ones for skin tissue analysis comprising: contacting a skin tissue array with at least one test agent; measuring a plurality of datasets following the contacting; mapping the plurality of datasets based on a scoring panel result; and generating at least one threshold criteria for selecting the therapeutic agent from the at least one test agent based on the mapped datasets. Such innovations described herein provide for an ex vivo model tissue system and use of the model tissue system for analytical activities such as screening of nutrients, pharmaceutical activity, and toxicity in tissue samples.