IMPROVED METHODS OF PREPARING DIFFERENT MESODERM CELL TYPES
개요
출원인
Children's Hospital Medical Center; RIKEN
발명자
Aaron M. ZORN; Lu HAN; Keishi KISHIMOTO; Mitsuru MORIMOTO
IPC 분류
CPC 분류
Disclosed herein are improved in vitro methods of making splanchnic mesoderm cell types and subtypes thereof from pluripotent cells. These methods can be used to produced improved foregut- and hindgut-derived organoids containing enriched mesenchyme, which enhances organoid viability, growth, and maturation, both in in vitro culture and in vivo transplantation.
원문 (중국어)
Disclosed herein are improved in vitro methods of making splanchnic mesoderm cell types and subtypes thereof from pluripotent cells. These methods can be used to produced improved foregut- and hindgut-derived organoids containing enriched mesenchyme, which enhances organoid viability, growth, and maturation, both in in vitro culture and in vivo transplantation.