Reagents and Methods for Identifying Pregnancy Risk
개요
발명자
Edward E Winger; Jane L Reed
IPC 분류
CPC 분류
This disclosure relates to miRNA-related reagents and methods for identifying health risks during pregnancy. In preferred embodiments, the miRNAs are selected from those disclosed herein that in a pregnant human being indicate an increased risk of developing a placental bed disorder as compared to the control sample. In some preferred embodiments, such miRNAs are selected from the group consisting of hsa-miR-150-5p, hsa-let-7g-5p, hsa-miR-16-5p, hsa-miR-29a-3p, hsa-let-7f-5p, hsa-miR-15b-5p, hsa-let-7i-5p, hsa-miR-26b-5p, hsa-miR-223-3p, hsa-miR-21-5p, hsa-miR-23a-3p, hsa-miR-142-3p, hsa-miR-19b-3p, hsa-let-7a-5p, hsa-miR-22-3p, hsa-miR-29c-3p, hsa-miR-342-3p, hsa-miR-25-3p, hsa-miR-24-3p, and hsa-miR-17-5p.
원문 (중국어)
This disclosure relates to miRNA-related reagents and methods for identifying health risks during pregnancy. In preferred embodiments, the miRNAs are selected from those disclosed herein that in a pregnant human being indicate an increased risk of developing a placental bed disorder as compared to the control sample. In some preferred embodiments, such miRNAs are selected from the group consisting of hsa-miR-150-5p, hsa-let-7g-5p, hsa-miR-16-5p, hsa-miR-29a-3p, hsa-let-7f-5p, hsa-miR-15b-5p, hsa-let-7i-5p, hsa-miR-26b-5p, hsa-miR-223-3p, hsa-miR-21-5p, hsa-miR-23a-3p, hsa-miR-142-3p, hsa-miR-19b-3p, hsa-let-7a-5p, hsa-miR-22-3p, hsa-miR-29c-3p, hsa-miR-342-3p, hsa-miR-25-3p, hsa-miR-24-3p, and hsa-miR-17-5p.