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기록

Reagents and Methods for Identifying Pregnancy Risk

발명심사 중
21청구항 · 13 독립항
§ Ⅰ

개요

발명자

Edward E Winger; Jane L Reed

IPC 분류

C12Q 1/6883

CPC 분류

C12Q1/6883C12Q2600/118C12Q2600/158C12Q2600/178

This disclosure relates to miRNA-related reagents and methods for identifying health risks during pregnancy. In preferred embodiments, the miRNAs are selected from those disclosed herein that in a pregnant human being indicate an increased risk of developing a placental bed disorder as compared to the control sample. In some preferred embodiments, such miRNAs are selected from the group consisting of hsa-miR-150-5p, hsa-let-7g-5p, hsa-miR-16-5p, hsa-miR-29a-3p, hsa-let-7f-5p, hsa-miR-15b-5p, hsa-let-7i-5p, hsa-miR-26b-5p, hsa-miR-223-3p, hsa-miR-21-5p, hsa-miR-23a-3p, hsa-miR-142-3p, hsa-miR-19b-3p, hsa-let-7a-5p, hsa-miR-22-3p, hsa-miR-29c-3p, hsa-miR-342-3p, hsa-miR-25-3p, hsa-miR-24-3p, and hsa-miR-17-5p.

원문 (중국어)

This disclosure relates to miRNA-related reagents and methods for identifying health risks during pregnancy. In preferred embodiments, the miRNAs are selected from those disclosed herein that in a pregnant human being indicate an increased risk of developing a placental bed disorder as compared to the control sample. In some preferred embodiments, such miRNAs are selected from the group consisting of hsa-miR-150-5p, hsa-let-7g-5p, hsa-miR-16-5p, hsa-miR-29a-3p, hsa-let-7f-5p, hsa-miR-15b-5p, hsa-let-7i-5p, hsa-miR-26b-5p, hsa-miR-223-3p, hsa-miR-21-5p, hsa-miR-23a-3p, hsa-miR-142-3p, hsa-miR-19b-3p, hsa-let-7a-5p, hsa-miR-22-3p, hsa-miR-29c-3p, hsa-miR-342-3p, hsa-miR-25-3p, hsa-miR-24-3p, and hsa-miR-17-5p.