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案件記録

TREATMENT OF CNS DISEASES WITH sGC STIMULATORS

発明審査中
19請求項 · 4 独立
§ Ⅰ

案件概要

発明者

Joon Jung; Thomas Wai-Ho Lee; Rajesh R. Iyengar; Nicholas Robert Perl; Peter Germano; Maria D. Ribadeneira; Kim Tang

IPC分類

A61K 31/437A61K 31/5025A61K 31/506A61K 31/519A61P 25/28

CPC分類

A61K31/437A61K31/5025A61K31/506A61K31/519A61P25/28

The present disclosure relates to the use of stimulators of soluble guanylate cyclase (sGC), pharmaceutically acceptable salts thereof and pharmaceutical formulations or dosage forms comprising them, alone or in combination with one or more additional agents, for the treatment of various CNS diseases, wherein an increase in sGC stimulation, or an increase in the concentration of nitric oxide (NO), or cyclic guanosine 3′5′-monophosphate (cGMP) or both, or an upregulation of the NO pathway is desirable.

原文(中国語)

The present disclosure relates to the use of stimulators of soluble guanylate cyclase (sGC), pharmaceutically acceptable salts thereof and pharmaceutical formulations or dosage forms comprising them, alone or in combination with one or more additional agents, for the treatment of various CNS diseases, wherein an increase in sGC stimulation, or an increase in the concentration of nitric oxide (NO), or cyclic guanosine 3′5′-monophosphate (cGMP) or both, or an upregulation of the NO pathway is desirable.

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