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案件記録

COMPOUNDS, COMPOSITIONS, AND METHODS FOR REDUCING PRODUCTION OF TRIMETHYLAMINE

発明審査中
31請求項 · 1 独立
§ Ⅰ

案件概要

発明者

Stanley L. Hazen; James T. Anderson

IPC分類

C7C 219/6A61K 31/45A61K 31/122A61K 31/145A61K 31/202A61K 31/221A61K 31/225A61K 31/245A61K 31/265A61K 31/575A61K 31/60A61K 33/245A61K 35/A61K 35/741A61K 36/63A61K 36/68A61K 36/88C7C 219/28C7C 307/2

CPC分類

C7C219/6A61K31/45A61K31/122A61K31/145A61K31/202A61K31/221A61K31/225A61K31/245A61K31/265A61K31/575A61K31/60A61K33/245A61K35/741A61K36/63A61K36/68A61K36/88C7C219/28C7C307/2A61K2035/115

Provided herein are substituted quaternary amine salt compounds and compositions thereof for inhibiting production of trimethylamine (TMA), as well as inhibiting the conversion of choline to trimethylamine, and such compounds, and compositions thereof, utilized for treating for example, kidney disease, diabetes and cardiovascular disease, disorders that are associated with inhibiting the conversion of choline to trimethylamine.

原文(中国語)

Provided herein are substituted quaternary amine salt compounds and compositions thereof for inhibiting production of trimethylamine (TMA), as well as inhibiting the conversion of choline to trimethylamine, and such compounds, and compositions thereof, utilized for treating for example, kidney disease, diabetes and cardiovascular disease, disorders that are associated with inhibiting the conversion of choline to trimethylamine.

外部リソース