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기록

TRIAZOLE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR D

발명심사 중
390청구항 · 7 독립항
§ Ⅰ

개요

발명자

Adam YEAGER; Marion LANIER; Brandon SELFRIDGE; Liming HUANG; Esther MARTINBOROUGH; Marcus BOEHM

IPC 분류

C7D 413/14A61K 31/4192A61K 31/4196A61K 31/427A61K 31/437A61K 31/4439A61K 31/444A61K 31/506A61K 31/519A61K 31/5377C7D 249/6C7D 401/12C7D 401/14C7D 403/10C7D 403/12C7D 403/14C7D 405/12C7D 405/14C7D 409/12C7D 409/14C7D 413/12C7D 417/12C7D 417/14C7D 471/4C7D 487/4

CPC 분류

C7D413/14A61K31/4192A61K31/4196A61K31/427A61K31/437A61K31/4439A61K31/444A61K31/506A61K31/519A61K31/5377C7D249/6C7D401/12C7D401/14C7D403/10C7D403/12C7D403/14C7D405/12C7D405/14C7D409/12C7D409/14C7D413/12C7D417/12C7D417/14C7D471/4C7D487/4

Provided is a compound having the structure of Formula (I): or a pharmaceutically acceptable salt, hydrate, solvate or isotope thereof, wherein A, B, R, R, R, R, R, R, R, m, n, p, and y are as defined herein, for use in methods for modulating MRGPRD or for treating a MRGPRD dependent condition. Pharmaceutical compositions containing such compounds, as well as to compounds themselves, are also provided.

원문 (중국어)

Provided is a compound having the structure of Formula (I): or a pharmaceutically acceptable salt, hydrate, solvate or isotope thereof, wherein A, B, R, R, R, R, R, R, R, m, n, p, and y are as defined herein, for use in methods for modulating MRGPRD or for treating a MRGPRD dependent condition. Pharmaceutical compositions containing such compounds, as well as to compounds themselves, are also provided.