SYNTHETIC HEXASACCHARIDES MIMICS OF HEPARIN SHOWING HEPARANASE INHIBITION ACTIVITY
案件概要
出願人
CENTRO ALTA TECNOLOGIA ISTITUTO DI RICERCHE CHIMICHE E BIOCHIMICHE G. RONZONI S.R.L.
発明者
Annamaria NAGGI; Maurice PETITOU; Ming Hong NI
IPC分類
CPC分類
The present invention is directed to hexasaccharides mimetics of heparins presenting remarkable heparanase inhibition activity. The compounds have formula (I), wherein Ris selected from the group consisting of NH, NHSONa, NHAc; Ris selected from the group consisting of NH, NHSONa, NHAc; Ris selected from the group consisting of Bn, H; Ris selected from the group consisting of Ac, H, SONa; Ris CONa; Ris selected from the group consisting of Me, Ethyl, Alkyl, alkyl azide, alkynyl, cholestanol aglycon; Ris selected from the group consisting of CHOH, COOH.
原文（中国語）
The present invention is directed to hexasaccharides mimetics of heparins presenting remarkable heparanase inhibition activity. The compounds have formula (I), wherein Ris selected from the group consisting of NH, NHSONa, NHAc; Ris selected from the group consisting of NH, NHSONa, NHAc; Ris selected from the group consisting of Bn, H; Ris selected from the group consisting of Ac, H, SONa; Ris CONa; Ris selected from the group consisting of Me, Ethyl, Alkyl, alkyl azide, alkynyl, cholestanol aglycon; Ris selected from the group consisting of CHOH, COOH.
外部リソース