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案件記録

ENHANCING NEURONAL DIFFERENTIATION OF VENTRAL MIDBRAIN NEURAL PROGENITOR CELLS

発明審査中
2閲覧数
15請求項 · 5 独立
§ Ⅰ

案件概要

発明者

Djordje Djordjevic; Jonathan Niclis; Josefine Raagaard Christiansen

IPC分類

C12N 5/793

CPC分類

C12N5/619C12N2500/38C12N2501/119C12N2501/13C12N2501/41C12N2501/42C12N2501/727C12N2506/2C12N2533/52

The present invention relates to a method for directing differentiation of ventral midbrain NSCs into neurons comprising contacting a cell population comprising ventral midbrain NSCs with an inhibitor of MEK signaling and an inhibitor of NOTCH signaling, wherein the ventral midbrain NSCs co-express the markers FOXA2, LMX1A, EN1, OTX2, 5 and SOX2.

原文(中国語)

The present invention relates to a method for directing differentiation of ventral midbrain NSCs into neurons comprising contacting a cell population comprising ventral midbrain NSCs with an inhibitor of MEK signaling and an inhibitor of NOTCH signaling, wherein the ventral midbrain NSCs co-express the markers FOXA2, LMX1A, EN1, OTX2, 5 and SOX2.

外部リソース