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MULTI-PASS SOFTWARE-ACCELERATED GENOMIC READ MAPPING ENGINE

发明专利审中
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20权利要求 · 3 独立
§ Ⅰ

卷宗概要

发明人

Guillaume Alexandre Pascal RIZK

IPC 分类

G16B 30/10G16B 20/G16B 20/20G16B 30/G16B 40/20

CPC 分类

G16B30/10G16B20/G16B20/20G16B30/G16B40/20

Software-accelerated genomic data read mapping includes commencing iterative performance of operations for the software accelerated genomic data read mapping to map a genomic data read to a reference genome. The operations include obtaining a next k-mer seed from a genomic data read, generating a genomic signature based on the next k-mer seed, determining a reference sequence location using a hash data structure, determining a number of mismatches of the next k-mer seed, based on determining the number of mismatches satisfies a mismatch threshold, terminating the iterative performance of the operations, and selecting an actual alignment for the genomic data read based on the obtained next k-mer seed.

原文(中文)

Software-accelerated genomic data read mapping includes commencing iterative performance of operations for the software accelerated genomic data read mapping to map a genomic data read to a reference genome. The operations include obtaining a next k-mer seed from a genomic data read, generating a genomic signature based on the next k-mer seed, determining a reference sequence location using a hash data structure, determining a number of mismatches of the next k-mer seed, based on determining the number of mismatches satisfies a mismatch threshold, terminating the iterative performance of the operations, and selecting an actual alignment for the genomic data read based on the obtained next k-mer seed.