PHARMACOGENOMICS INDUCED PROTEIN FUNCTION OF THERAPEUTIC TARGETS
卷宗概要
申请人
International Business Machines Corporation
发明人
ARITRA BOSE; FILIPPO UTRO; Laxmi Parida
IPC 分类
CPC 分类
A set of candidate drugs is selected based on one or more outcomes related to one or more diseases and variants linked with the selected set of candidate drugs are obtained. One or more protein sequences related to the selected set of candidate drugs are collated. Pairs of variants and protein sequences are generated for each drug of the set of candidate drugs. A contrastive learning model is trained using the generated pairs of variants and protein sequences and a downstream task is performed using the contrastive learning model.
原文（中文）
A set of candidate drugs is selected based on one or more outcomes related to one or more diseases and variants linked with the selected set of candidate drugs are obtained. One or more protein sequences related to the selected set of candidate drugs are collated. Pairs of variants and protein sequences are generated for each drug of the set of candidate drugs. A contrastive learning model is trained using the generated pairs of variants and protein sequences and a downstream task is performed using the contrastive learning model.