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№ US20260001967A1发明专利

审中

SYNTHETIC HEXASACCHARIDES MIMICS OF HEPARIN SHOWING HEPARANASE INHIBITION ACTIVITY

The present invention is directed to hexasaccharides mimetics of heparins presenting remarkable heparanase inhibition activity. The compounds have formula (I), wherein Ris selected from the group consisting of NH, NHSONa, NHAc; Ris selected from the group consisting of NH, NHSONa, NHAc; Ris selected from the group consisting of Bn, H; Ris selected from the group consisting of Ac, H, SONa; Ris CONa; Ris selected from the group consisting of Me, Ethyl, Alkyl, alkyl azide, alkynyl, cholestanol aglycon; Ris selected from the group consisting of CHOH, COOH.

❖CENTRO ALTA TECNOLOGIA ISTITUTO DI RICERCHE CHIMICHE E BIOCHIMICHE G. RONZONI S.R.L.Annamaria NAGGI; Maurice PETITOU; Ming Hong NI§ 1/6 权利要求C8B 37/23

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原始名称记载: CENTRO ALTA TECNOLOGIA ISTITUTO DI RICERCHE CHIMICHE E BIOCHIMICHE G. RONZONI S.R.L.

SYNTHETIC HEXASACCHARIDES MIMICS OF HEPARIN SHOWING HEPARANASE INHIBITION ACTIVITY