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Original name record: 延安大学; 三亚崖州湾创新发展中心有限公司

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1 indexed patent records

№ CN121378260AInvention
Active

一种咪唑-脱氧鸭嘴花碱衍生物及其制备方法和应用

本发明公开了一种咪唑‑脱氧鸭嘴花碱衍生物及其制备方法和应用，所述咪唑‑脱氧鸭嘴花碱衍生物的结构通式如式I所示：……式I；式I中，R1和R2分别为氢、甲基、乙基、丙基、苯基或苄基；本发明提供的咪唑‑脱氧鸭嘴花碱衍生物，其对乙酰胆碱酯酶（AChE）、β‑淀粉样蛋白（Aβ）和MAO‑B均具有较强的抑制作用，进而能够实现对AD的治疗，有望成为多靶标抗AD的先导结构。

❖延安大学; 三亚崖州湾创新发展中心有限公司杜宏涛; 马芳; 李娜; 阎岩; 毛仁俊; 王延峰§ 2/10 ClaimsC07D 487/04 (2006.01), A61P 25/28 (2006.01)10