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Original name record: 温州医科大学细胞生长因子药物和蛋白制剂国家工程研究中心

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1 indexed patent records

№ CN121343010AInvention
Active

一种长效成纤维细胞生长因子21融合蛋白及其应用

本发明涉及一种长效成纤维细胞生长因子21融合蛋白及其应用。本发明的融合蛋白的氨基酸序列如SEQ ID No. 1所示，其可以有效延长成纤维细胞生长因子21的半衰期，进而使成纤维细胞生长因子21具备了长效性，并且在此基础上，融合蛋白保留了成纤维细胞生长因子21的已知功能。此外本发明还发现，融合蛋白Nb‑FGF21能够显著改善皮肤色斑，可以基于此来治疗皮肤色斑。

❖温州医科大学细胞生长因子药物和蛋白制剂国家工程研究中心李校堃; 苏志坚; 李昭宇; 林丽; 冯娅§ 1/5 ClaimsC07K 19/00 (2006.01), C12N 15/62 (2006.01), A61K 38/18 (2006.01) +410