治疗癌症的方法
本文公开了使用CDK12/13抑制剂或降解剂与免疫检查点阻断(ICB)疗法的组合治疗癌症的方法。本文还公开了使用CDK12/13抑制剂或降解剂增强对ICB疗法的反应的方法。本文进一步公开了使用CDK12/13表达作为ICB疗法的临床结局的预测生物标记物的方法。
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